In s. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase

HIGHLIGHTS

  • who: Maurizio D. Baroni from the Department of Biology, University of Padua, Padua, Italy have published the Article: In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase, in the Journal: (JOURNAL)
  • what: The authors show that HCA was able to limit the accumulation of ROS in aged yeast cells challenged with hydrogen peroxide.
  • future: The data together with published biochemical analyses indicate that HCA may act with multiple mechanisms together with ACLY repression and allowed the authors to propose an integrated mechanistic model as a basis for future . . .

     

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