In silico binding of 2-aminocyclobutanones to sars-cov-2 nsp13 helicase and demonstration of antiviral activity

HIGHLIGHTS

  • who: Thahani S. Habeeb Mohammad and colleagues from the Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago, IL, USA have published the article: In Silico Binding of 2-Aminocyclobutanones to SARS-CoV-2 Nsp13 Helicase and Demonstration of Antiviral Activity, in the Journal: (JOURNAL) of 23/01/2023
  • what: The authors confirmed in silico inhibitory potencies with predicted strong target-ligand interactions against SARS-CoV-2 Nsp13 helicase, and subsequently demonstrated anti-viral efficacies of these u03b1-amino cyclobutanones that the authors report herein, revealing a new class of small_molecule SARS-CoV-2 Nsp13 . . .

     

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