In silico derivation of hla-specific alloreactivity potential from whole exome sequencing of stem-cell transplant donors and recipients: understanding the quantitative immunobiology of allogeneic transplantation

HIGHLIGHTS

  • who: Amir Ahmed Toor from the Stem Cell, Center, Virginia Commonwealth University, Richmond, VA, USA have published the article: In silico derivation of HLA-specific alloreactivity potential from whole exome sequencing of stem-cell transplant donors and recipients: understanding the quantitative immunobiology of allogeneic transplantation, in the Journal: (JOURNAL)
  • what: In this paper, the putative mHA in HLA-matched DRP and the in silico determined HLA class I binding affinity of these peptides is explored utilizing a bioinformatic approach based on exome sequencing of donors and recipients of SCT. The work demonstrates that the number . . .

     

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