HIGHLIGHTS
- who: Hafsa Amat-ur-Rasool et al. from the School of Medicine, Royal Derby Hospital Centre, University of Nottingham, Derby , DT, UK have published the Article: In Silico Design of Dual-Binding Site Anti-Cholinesterase Phytochemical Heterodimers as Treatment Options for Alzheimer’s Disease, in the Journal: (JOURNAL) of 29/Dec/2021
SUMMARY
Potential control of AChE activity via dual inhibitory binding_site occupancy has led to the generation of hybrid ligands separated by suitable linkers or spacers. Rational synthesis of dual-binding_site ligands has included drug candidates with inhibitory potency against both AChE . . .
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