In-silico studies to recognize repurposing therapeutics toward arginase-i inhibitors as a potential onco-immunomodulators

HIGHLIGHTS

  • who: April and collaborators from the Shanghai Jiao Tong, China have published the article: In-silico studies to recognize repurposing therapeutics toward arginase-I inhibitors as a potential onco-immunomodulators, in the Journal: (JOURNAL)
  • what: The QSAR VS. predicts the arginase I inhibitory activity (pIC50) of all 1615 FDA compounds, of which 112 have a pIC50 in the range of 8.07-10.023 M. Therefore, a molecular docking study was conducted to determine the binding pattern of these 112 FDA molecules. The authors assess the excretion property of nystatin to estimate the drug`s . . .

     

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