In situ vaccination using unique tlr9 ligand k3-spg induces long-lasting systemic immune response and synergizes with systemic and local immunotherapy

HIGHLIGHTS

  • who: Hirokazu Okada from the DepartmentKyoto University have published the paper: In situ vaccination using unique TLR9 ligand K3-SPG induces long-lasting systemic immune response and synergizes with systemic and local immunotherapy, in the Journal: Scientific Reports Scientific Reports of 20/09/2021
  • what: To exclude dead cells from the analysis, a fixable viability stain 510 (BD Biosciences) was used.
  • how: The authors investigated the antitumor effect of K3-SPG-ISV using a syngeneic pancreatic cancer model. In this study focusing on the clinical feasibility and advantages of ISV as mentioned in . . .

     

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