HIGHLIGHTS
- who: PD-L and colleagues from the DepartmentNephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA have published the paper: in triple-negative breast cancer, in the Journal: (JOURNAL)
- what: The authors demonstrate a potentially novel mechanism by which promotes the epithelial-mesenchymal transition (EMT) in triple-negative breast cancer (TNBC) cells by suppressing the destruction of the EMT transcription factor Snail. directly binds to and inhibits the tyrosine phosphatase PTP1B thus preserving p38-MAPK activity that phosphorylates and inhibits glycogen synthase kinase 3β (GSK3β). The authors demonstrate that PD-L1 facilitates the EMT in TNBC . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.