In vitro and in silico biological studies of 4-phenyl-2-quinolone (4-pq) derivatives as anticancer agents

HIGHLIGHTS

  • who: Yi-Fong Chen and collaborators from the Graduate Institute of Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Medical University, Taiwan have published the Article: In Vitro and In Silico Biological Studies of 4-Phenyl-2-Quinolone (4-PQ) Derivatives as Anticancer Agents, in the Journal: Molecules 2023, 555 of 21/Dec/2022
  • what: In this study, molecular docking was simulated to investigate the binding modalities of 4-PQ derivatives against tubulin using AutoDock4 and AutoDock Vina software . The authors identified 4-PQ compounds with extensive interactions with amino_acids of . . .

     

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