In vitro and in vivo anti−toxoplasma activities of hdac inhibitor panobinostat on experimental acute ocular toxoplasmosis

HIGHLIGHTS

  • who: Yu Zhang from the Nanjing Agricultural University, China have published the research work: In vitro and in vivo antiu2212Toxoplasma activities of HDAC inhibitor Panobinostat on experimental acute ocular toxoplasmosis, in the Journal: (JOURNAL)
  • what: The authors have investigated a novel HDAC inhibitor, LBH589, against the infection of T. gondii. The authors have evaluated the anti-T. gondii and therapeutic effect of LBH589 on OT for the first time, which was mainly used in cutaneous T-cell lymphoma (CTCL), Hodgkin`s lymphoma as well as acute myeloid leukemia pyrimethamine and sulfadiazine (P-S). The research . . .

     

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