In vitro co-culture systems of hepatic and intestinal cells for cellular pharmacokinetic and pharmacodynamic studies of capecitabine against colorectal cancer

HIGHLIGHTS

• who: Chun Ge from the (UNIVERSITY) have published the Article: In vitro co-culture systems of hepatic and intestinal cells for cellular pharmacokinetic and pharmacodynamic studies of capecitabine against colorectal cancer, in the Journal: (JOURNAL)
• what: The authors aimed to establish a novel in vitro system to effectively assess the PK and PD of these kinds of prodrugs. The simple and costu2011effective co-culture models with both CRC and hepatocarcinoma cells could mimic the in vivo process of a prodrug dependent on metabolic conversion to active metabolites in the liver providing a u2020 and have . . .
  

   

  

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