In vitro crispr/cas9 transfection and gene-editing mediated by multivalent cationic liposome-dna complexes

HIGHLIGHTS

  • who: Diana A. Sousa and colleagues from the CEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, have published the Article: In Vitro CRISPR/Cas9 Transfection and Gene-Editing Mediated by Multivalent Cationic Liposome-DNA Complexes, in the Journal: Pharmaceutics 2022, 14, x FOR PEER REVIEW of 19/05/2022
  • what: The authors report on the preparation and application of two systems (i.e. lipoplexes) for gene delivery. The authors showed that replacing DOTAP with MVL5 in simple two-lipid formulations leads to a pronounced improvement in the transfection of Cas9/sgRNA plasmids . . .

     

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