In vitro evaluation and mitigation of niclosamide’s liabilities as a covid-19 treatment

HIGHLIGHTS

  • who: Jesse W. Wotring et al. from the Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA have published the research: In Vitro Evaluation and Mitigation of Niclosamide’s Liabilities as a COVID-19 Treatment, in the Journal: Vaccines 2022, 10, 1284. of /2022/
  • what: The authors used high-content imaging-based immunofluorescence assays in two different cell models to assess these limitations and evaluate the potential for using niclosamide as a COVID-19 antiviral. The authors show that despite promising preliminary reports the antiviral efficacy of niclosamide overlaps with . . .

     

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