In vitro evaluation of isoniazid derivatives as potential agents against drug-resistant tuberculosis

HIGHLIGHTS

  • who: Derivatives as Potential Agents and collaborators from the Gilead, United States University College London have published the Article: In vitro Evaluation of Isoniazid Derivatives as Potential Agents Against Drug-Resistant Tuberculosis, in the Journal: (JOURNAL)
  • what: Considering all the above, the authors provide a detailed biophysical study of the interaction of a series of INH derivatives-Figure 1 with this plasma_protein and a correlation study with the corresponding lipophilicity is undertaken. The authors intended to assess the toxicity of these INH derivatives as a pre-screening approach to evaluate the suitability of these compounds . . .

     

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