In vitro-in vivo correlation of posaconazole-amphotericin b combination against candida albicans: in vitro interacting concentrations are associated with in vivo free drug levels

HIGHLIGHTS

  • who: Joseph Meletiadis et al. from the Clinical Microbiology Laboratory, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece have published the research work: In Vitro-In Vivo Correlation of Posaconazole-Amphotericin B Combination against Candida albicans: In Vitro Interacting Concentrations Are Associated with In Vivo Free Drug Levels, in the Journal: (JOURNAL) of 24/Nov/1986
  • what: Regarding the monotherapies, the analysis showed that fungal burden was reduced compared to controls by 16 u00b1 3% and 100% at the highest doses of posaconazole (0.9 mg/kg) and amphotericin B . . .

     

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