HIGHLIGHTS
- who: Akash K. Kaushik et al. from the (UNIVERSITY) have published the research: In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma, in the Journal: (JOURNAL) of 16/Dec/2022
SUMMARY
Renal cell carcinomas (RCC) are characterized by mutations in genes that regulate intermediary_metabolism, resulting in metabolic dependencies that have been proposed as therapeutic targets. An important bottleneck in cancer metabolism studies is the relative lack of information about pathway activity in_vivo. By infusing patients with cancer intraoperatively with 13C-labeled nutrients and examining 13C enrichment in . . .
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