In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice

HIGHLIGHTS

  • who: Carine Bouffi from the (UNIVERSITY) have published the Article: In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice, in the Journal: (JOURNAL)
  • what: To overcome this limitation, here the authors report a next-generation HIO system containing human immune cells, obtained by growing HIOs in mice with a humanized immune system. The authors aimed to bridge the gap by integrating human immune cells in a human intestinal tissue. The authors aimed to M cells are induced in transplanted HIOs after microbial exposure M cells are expressed in the epithelium . . .

     

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