In vivo distribution and therapeutic efficacy of radioiodine- labeled ph-low insertion peptide variant 3 in a mouse model of breast cancer

HIGHLIGHTS

• who: Breast Cancer and colleagues from the Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China have published the paper: In Vivo Distribution and Therapeutic Efficacy of Radioiodine- Labeled pH-Low Insertion Peptide Variant 3 in a Mouse Model of Breast Cancer, in the Journal: Molecular Imaging
• what: This study evaluates the distribution and therapeutic efficacy of radioiodine-labeled pHLIP variant 3 (Var3) in a mouse model of BC. This study showed that 131I-Var3pHLIP inhibited tumor growth in MDA-MB-231 xenografts through ionizing_radiation damage.
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