In vivo knockdown of intersectin-1s alters endothelial cell phenotype and causes microvascular remodeling in the mouse lungs

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  • who: Apoptosis ( et al. from the Department of Pharmacology, Rush University, WHarrison St., Chicago, IL, USA have published the research work: In vivo knockdown of intersectin-1s alters endothelial cell phenotype and causes microvascular remodeling in the mouse lungs, in the Journal: (JOURNAL)
  • what: The aim of this study was to elucidate the in_vivo effects of ECs apoptosis and impaired endocytic membrane trafficking caused by ITSN1s deficiency on mouse lung vasculature and lung homeostasis, using the lung-specific KDITSN mouse model the authors generated . The authors show that specific downregulation of ITSN-1s expression in . . .

     

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