In vivo mammalian alkaline comet assay: method adapted for genotoxicity assessment of nanomaterials

HIGHLIGHTS

• who: METHODS et al. from the Institute for Air Research, Kjelle, Norway, Department of Nutrition Institute of Basic Medical Sciences, University of Oslo, Oslo, Administration, Silver Spring, MD, United States have published the paper: In vivo Mammalian Alkaline Comet Assay: Method Adapted for Genotoxicity Assessment of Nanomaterials, in the Journal: (JOURNAL)
• what: The study should aim to identify the maximum tolerated dose (MTD) without evidence of studylimiting toxicity for the duration of the study period (e_g, no death or evidence of pain, suffering or distress of the animals; no suppression of body weight gain, hematopoietic . . .
  

   

  

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