HIGHLIGHTS
- who: Rana S. Moubarak from the University of Nebraska Medical Center, United States have published the article: In Vivo miRNA Decoy Screen Reveals miR-124a as a Suppressor of Melanoma Metastasis, in the Journal: (JOURNAL)
- what: Despite great advances in available screen strategies using miRNA inhibition via Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 in_vitro , this approach has proven challenging for efficient inhibition of miRNA biogenesis and function. To test this hypothesis, the authors aimed to conditionally induce miR-124a in melanoma cells after reaching distal organs. The experiment was terminated 36 days after . . .
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