HIGHLIGHTS
- who: Eric P. Souto from the Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, USA have published the paper: In Vivo Modeling of Human Breast Cancer Using Cell Line and Patient-Derived Xenografts, in the Journal: (JOURNAL)
- what: For the purposes of this review, the authors will focus exclusively on human cells grown in_vivo. For this study design, 20-30 PDX models are chosen either randomly, or rationally based on the drugs being used.
- how: Another model was developed in 2012 by mutating the IL2Ru03b3 gene which leads to . . .
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