HIGHLIGHTS
- who: Ruofan Yu from the College Houston, TX, USAUniversity of have published the paper: Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: To demonstrate the method `s ability to discover previously unidentified genes and pathways involved in aging, the authors focused on characterizing one aging regulator that was identified from the screening, histone deacetylase complex HDA. As carbohydrate metabolism genes were significantly upregulated in hda1u0394, the authors aimed to identify the specific pathway that was involved. Based on these results, the authors propose the following . . .
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