Inactivation of zscan18 by promoter hypermethylation drives the proliferation via attenuating tp53inp2-mediated autophagy in gastric cancer cells

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  • who: Bin Li from the Department of Surgery, Tianjin Medical University Research Center for, Tianjin, Peopleu2019s Republic of China have published the paper: Inactivation of ZSCAN18 by promoter hypermethylation drives the proliferation via attenuating TP53INP2-mediated autophagy in gastric cancer cells, in the Journal: (JOURNAL)
  • what: ZSCAN18 is frequently hypermethylated in primary GC and is associated with poor survival To explore the regulation mechanism of ZSCAN18 in GC, the authors focused on epigenetic alterations, especially DNA promoter methylation. The authors provide substantial evidence of a suppressive effect of ZSCAN18 on GC.
  • how: The . . .

     

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