Inactivity and ca2+ signaling regulate synaptic compensation in motoneurons following hibernation in american bullfrogs

HIGHLIGHTS

• who: Tanya Zubov from the DepartmentThe University have published the research work: Inactivity and Ca2+ signaling regulate synaptic compensation in motoneurons following hibernation in American bullfrogs, in the Journal: Scientific Reports Scientific Reports
• what: The authors demonstrate that increases in synaptic drive are present at 2 weeks into aquatic hibernation, which saturate a new steady-state level (Fig 1C).
• how: The authors compared average miniature excitatory postsynaptic current amplitude in slices (mESPCs) following network inactivity induced by TTX to Time Controls (control preparations with rhythmic activity present for 16 h at 22 °C . . .
  

   

  

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