Inconsistencies in modeling the ef cacy of the oncolytic virus hsv1716 reveal potential predictive biomarkers for tolerability

HIGHLIGHTS

  • who: HSV et al. from the Department of Oncology and Metabolism, University of Sheffield, Sheffield, United Kingdom, Virtuu Biologics/Sorrento have published the article: Inconsistencies in Modeling the Ef cacy of the Oncolytic Virus HSV1716 Reveal Potential Predictive Biomarkers for Tolerability, in the Journal: (JOURNAL)
  • how: The authors investigated the clinical relevance of this finding using pleural effusion samples from a phase I/IIa trial of intrapleural administration of HSV1716 which reported good tolerability among patients as well as an antitumor immune_response (Danson et_al 2020). The data are in accord with this theory yet rather . . .

     

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