Incorporation of a tgf-β2-inhibiting oligodeoxynucleotide molecular adjuvant into a tumor cell lysate vaccine to enhance antiglioma immunity in mice

HIGHLIGHTS

  • who: Liqun Tu and colleagues from the University of Maryland, United States have published the Article: Incorporation of a TGF-u03b22-inhibiting oligodeoxynucleotide molecular adjuvant into a tumor cell lysate vaccine to enhance antiglioma immunity in mice, in the Journal: (JOURNAL)
  • how: In this study TIO3 was used as an adjuvant in a formulation with the glioma TCL which was used to investigate the antitumor effects of TGF-b2 inhibition in mouse GL261 glioma models. The results indicated that TIO3-TCL regulates the activation of potent glioma-specific cytotoxic T lymphocytes and prolongs the survival . . .

     

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