HIGHLIGHTS
- who: Sian O` Brien from the Institute of Cardiovascular Science, University of Birmingham, Birmingham, UK have published the Article: Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels, in the Journal: (JOURNAL)
- what: The aims of this study were to robustly interrogate differences in biophysical properties of ventricular and atrial INa (inclusive of measurements at physiological membrane potentials), their effects on conduction, and examine chamber specific responses to flecainide. The authors show that atrial peak INa density is differentially influenced by resting membrane potential, more so than observed in the ventricular . . .
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