Increased circulating uric acid aggravates heart failure via impaired fatty acid metabolism

HIGHLIGHTS

  • who: Bowen Lou from the University, Xiu2019an, Shaanxi, China have published the research: Increased circulating uric acid aggravates heart failure via impaired fatty acid metabolism, in the Journal: (JOURNAL)
  • what: The aims of this study were (i) to assess whether SUA levels would be elevated in HF patients compared with control subjects; (ii) to evaluate the association between SUA, FFA levels and cardiac remodelling and dysfunction; (iii) to determine whether SUA would regulate FFA in_vitro and vivo; and_(iv) to elucidate the molecular mechanism regarding SUA induced lipid metabolic impairment during HF progression. The authors . . .

     

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