Increased frequency of tigit+ cd4 t cell subset in autoantibody-positive first-degree relatives of patients with rheumatoid arthritis

HIGHLIGHTS

  • who: Vidyanand Anaparti from the of Lübeck, Germany have published the research work: Increased frequency of TIGIT+ CD4 T Cell subset in autoantibody-positive first-degree relatives of patients with rheumatoid arthritis, in the Journal: (JOURNAL)
  • what: The authors used multiparametric flow cytometry to profile peripheral blood T and B lymphocytes in a cohort of RA autoantibody positive at-risk individuals and compared them to autoantibody negative individuals from the same population, and to RA patients with established disease. For the first time, the authors demonstrate an expanded TIGIT+ CD4 T_cell subset in aAb . . .

     

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