Increased gabab receptor signaling in a rat model for schizophrenia

HIGHLIGHTS

• who: Martijn M. Selten from the DepartmentRadboud University, Nijmegen, the Netherlands have published the research work: Increased GABAB receptor signaling in a rat model for schizophrenia, in the Journal: Scientific Reports Scientific Reports
• what: The authors compared the inhibitory system in the medial PFC (mPFC) of APO-SUS and APO-UNSUS rats at postnatal day (PND) 20-22. While basal synaptic transmission onto LII/III pyramidal cells was not different between the two rat lines, the authors report a decrease in the paired-pulse ratio in APO-SUS rats at longer (u2265u200b150 ms) intervals compared . . .
  

   

  

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