Increased gene targeting in hyper-recombinogenic lymphoblastoid cell lines leaves unchanged dsb processing by homologous recombination

HIGHLIGHTS

• who: Emil Mladenov and collaborators from the Division of Experimental Radiation Biology, Department of Radiation Therapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany have published the article: Increased Gene Targeting in Hyper-Recombinogenic LymphoBlastoid Cell Lines Leaves Unchanged DSB Processing by Homologous Recombination, in the Journal: (JOURNAL)
• what: The authors employ indirect immunofluorescence (IF) analysis of IR-induced RAD51 and γ-H2AX foci in DT40 and NALM6 cells to analyze their DSB repair characteristics and compare the results obtained to those of standard somatic cell lines - of normal tissue or tumor origin. The authors . . .
  

   

  

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