Increased glucocorticoid metabolism in diabetic kidney disease

HIGHLIGHTS

  • who: Daniel Ackermann and collaborators from the Department of Nephrology and Hypertension, University of Bern, Berne, Switzerland, Swiss Kidney have published the research: Increased glucocorticoid metabolism in diabetic kidney disease, in the Journal: PLOS ONE of April/15,/2021
  • what: Specifically the authors aimed first to demonstrate the presence of steroid hormones serving as alternative MR targets in type II diabetic patients with proteinuric kidney disease second whether MR selectivity was modified third to characterize MR and glucocorticoid receptor (GR) expression and activity in glomerular cell types exposed to eu- and hyperglycemic conditions fourth to . . .

     

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