HIGHLIGHTS
- who: Zuzana Parackova from the sur l`Inflammation, France University of Limerick, Ireland have published the paper: Increased histone citrullination in juvenile idiopathic arthritis, in the Journal: (JOURNAL)
- what: In this brief report, the authors demonstrate an enhancement of citrullination in patients with JIA due to elevated concentrations of citrullinated histone H3 (citH3) and the enzymes responsible for citrullination, namely PAD2 and PAD4. At first the main focus was on the antibodies directed to citrullinated proteins , but now it is realized citrullinating enzymes and citrullinated proteins may have important roles in the maintenance of the . . .
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