Increased intrinsic and synaptic excitability of hypothalamic pomc neurons underlies chronic stress-induced behavioral deficits

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  • who: Xing Fang from the Animals Wild-type C BL/ J, Pomc-Cre mice (Stock No005965), Pomc-GFP mice (Stock No., ) and Ai, mice (Stock No., ) were purchased from Jackson Laboratory (Bar Harbor, ME, USA). Ai, mice have a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven red fluorescent protein variant (tdTomato) and inserted into the Gt(ROSA) Sor locus (Gt(ROSA) Sortm14(CAG-tdTomato)). Ai, mice express robust tdTomato fluorescence following Cre-mediated recombination [36]. Male Pomc-Cre mice were crossed with Ai, tdTomato female mice to obtain PomcCre have published the research . . .

     

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