Increased levels of the parkinson’s disease-associated gene itpkb correlate with higher expression levels of -synuclein, independent of mutation status

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  • who: Francesca Di Leva et al. from the Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lu00fcbeck, Bolzano, Italy have published the research work: Increased Levels of the Parkinsonu2019s Disease-Associated Gene ITPKB Correlate with Higher Expression Levels of -Synuclein, Independent of Mutation Status, in the Journal: (JOURNAL)
  • what: To this work, the authors also demonstrated in a recently characterized new C. elegans model for PD (erals1), which is engineered to express human u03b1-synuclein, that the loss of function of Ife-2, the worm ortholog of ITPKB increases the formation of . . .

     

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