HIGHLIGHTS
- who: Jacqueline Surls et al. from the Department of Medicine, Division of Immunology and the Biostatistics Counseling Center, Uniformed Services University of the Health Sciences, Bethesda, Maryland have published the paper: Increased Membrane Cholesterol in Lymphocytes Diverts T-Cells toward an Inflammatory Response, in the Journal: (JOURNAL) of June/19,/2012
- what: Although the effect of cholesterol loading in APCs was not the focus of this study, the intimate mechanism by which cholesterol-rich rafts interferes with TLRs signaling and genetic regulation of IL-12 synthesis in APCs is worth being explored.
- how . . .
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