Increasing cure rates of solid tumors by immune checkpoint inhibitors

HIGHLIGHTS

  • who: Weijie Ma from the NY, USA Ellis Fischel Cancer Center, University of Missouri, Hospital Dr have published the research: Increasing cure rates of solid tumors by immune checkpoint inhibitors, in the Journal: (JOURNAL)
  • what: After the approval of the first immune checkpoint inhibitor (ICI), ipilimumab, targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4), initial investigations with ICIs were focused on salvage therapy for metastatic cancers. In this scenario, adjuvant pembrolizumab is commonly recommended based on the KEYNOTE-716 trial, although surveillance and enrollment in a clinical trial are reasonable alternatives.
  • future: As . . .

     

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