Independent presynaptic and postsynaptic mechanisms regulate endocannabinoid signaling at multiple synapses in the ventral tegmental area

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  • who: Arthur C., Riegel and Carl R., Lupica from the All protocols were conducted under National Institutes of Health Guidelines using the NIH handbook Animals in Research and were approved by the Institutional Animal Care and Use Committee (National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD)Recordings. Midbrain horizontal slices (, u242em) were prepared from adult male rats (Charles River Laboratories, Raleigh, NC) (, gm) as described previously (Williams et_al, ). Horizontal slices were placed in a recording chamber (0., ml) and submerged in continuously flowing physiological saline (34u00b0C) at a rate of , ml/min. The solution contained . . .

     

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