Indirect negative effect of mutant ataxin-1 on short- and long-term synaptic plasticity in mouse models of spinocerebellar ataxia type 1

HIGHLIGHTS

• who: Anton N. Shuvaev et al. from the Research Institute of Molecular Medicine and Pathobiochemistry, Krasnoyarsk State Medical University have published the paper: Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1, in the Journal: Cells 2022, 11, x FOR PEER REVIEW of 24/06/2022
• what: The authors report impairment of motor performance in both SCA1 models. The authors compare polyQ-Ataxin-1-evoked changes in cerebellar histology and synaptic plasticity between the SCA1 KI mouse and glia-targeted LVV-SCA1 . . .
  

   

  

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