Individualized medication based on pharmacogenomics and treatment progress in children with igav nephritis

HIGHLIGHTS

  • who: . et al. from the China Shanghai Jiao Tong University, China have published the paper: Individualized medication based on pharmacogenomics and treatment progress in children with IgAV nephritis, in the Journal: (JOURNAL)
  • what: In this review, the authors compare the current major international guidelines, summarize the current therapeutic use based on the analysis of the mechanisms of IgAV occurrence and explore potential therapeutic agents. The authors focus on the impact of genetic polymorphisms of cytochrome oxidase P450, drug transporters, and pharmacodynamic drug_targets on hormones and immunosuppressants, and analyze the individualized application of hormones and immunosuppressants . . .

     

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