HIGHLIGHTS
- who: Inducible and colleagues from the Northwestern University Toronto, Toronto, Ontario, Canada have published the research work: Inducible and Reversible Clock Gene Expression in Brain Using the tTA System for the Study of Circadian Behavior, in the Journal: (JOURNAL)
- what: The authors show that regulation of ClockD19 or Clockwt TG expression occurs with rapid kinetics of induction and repression, causing an immediate reversion of the mutant to wild-type (WT) phenotype, and vice versa, in a tissuespecific manner. The authors demonstrate that the CLOCK protein is an excellent indicator for the kinetics of Dox-dependent . . .
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