Inducing ferroptosis has the potential to overcome therapy resistance in breast cancer

HIGHLIGHTS

  • who: Xiaowen Qi and collaborators from the University of Texas MD Anderson have published the research: Inducing ferroptosis has the potential to overcome therapy resistance in breast cancer, in the Journal: (JOURNAL)
  • future: Ferroptosis offers a new direction in the treatment of breast cancer but how to avoid its side effects is still an open question.

SUMMARY

    Nuclear factor erythroid 2-related factor 2 (NRF2) exerts its antioxidant effects by upregulating the expression of genes related to iron and ROS metabolism and HO-1 to reduce ROS levels, increasing chemoresistance and . . .

     

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