HIGHLIGHTS
- who: Laura Padula and collaborators from the The University of Newcastle, Australia have published the paper: Induction of antigen specific intrahepatic CD8+ T cell responses by a secreted heat shock protein based gp96-Ig-PfCA malaria vaccine, in the Journal: (JOURNAL)
- what: The study shows that vaccination of mice and rhesus monkeys with HEK-293 cells transfected with gp96-Ig and two well-known Plasmodium falciparum CSP and AMA1 (PfCA) vaccine candidate antigens, induces liverinfiltrating, antigen specific, memory CD8+ T_cell responses. The authors show that the HEK-293 cell-based, gp96-Ig-PfCSP (C)-PfAMA . . .
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