Induction of atf4-regulated atrogenes is uncoupled from muscle atrophy during disuse in halofuginone-treated mice and in hibernating brown bears

HIGHLIGHTS

• who: Laura Cussonneau et al. from the Universitu00e9 Clermont Auvergne, INRAE, UNH UMR, CRNH Auvergne, Clermont-Ferrand, France have published the article: Induction of ATF4-Regulated Atrogenes Is Uncoupled from Muscle Atrophy during Disuse in Halofuginone-Treated Mice and in Hibernating Brown Bears, in the Journal: (JOURNAL)
• what: The authors show that ATF4-induced can be uncoupled from muscle atrophy.

SUMMARY

Activating transcription factor 4 (ATF4) is overexpressed in many conditions of muscle atrophy and is, therefore, considered as an atrogene, i.e., one of the genes with expression at the . . .

 



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