HIGHLIGHTS
- who: Kwinten Sliepen from the (UNIVERSITY) have published the article: Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate, in the Journal: (JOURNAL) of 24/02/2022
- what: The authors aimed to bring these regions in closer proximity by permutation, Nature Communications | 13:7271 sometimes referred to as circular permutation45, of E1 and E2 (E2E1) (Fig S1b). The promising immunogenicity results presented in this study and those obtained with mosaic nanoparticle vaccines against influenza and SARS-CoV-265,66,96 should provide an impetus to provide a regulatory framework . . .
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