HIGHLIGHTS
- who: A C Reis from the Institut Universidade Federal de Minas Gerais, Belo Horizonte, Brazil have published the research: Induction of eosinophil apoptosis by hydrogen peroxide promotes the resolution of allergic inflammation, in the Journal: (JOURNAL)
- what: The study provides evidence that H2O2 is released during allergic inflammation in a gp91phox - / - -dependent manner and induces a caspase-dependent proapoptotic effect in eosinophils, thus having a crucial role in the resolution of allergic inflammation. In this model, the inflammatory response was characterized by accumulation of leukocytes detectable at 12 h and that reached maximal at 24 . . .
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