Induction of high affinity monoclonal antibodies against sars-cov-2 variant infection using a dna prime-protein boost strategy

HIGHLIGHTS

  • who: Chen-Yi Chiang from the National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan have published the paper: Induction of high affinity monoclonal antibodies against SARS-CoV-2 variant infection using a DNA prime-protein boost strategy, in the Journal: (JOURNAL)
  • what: The authors report the discovery of mAb-S5 using a DNA prime-protein boost strategy, which is a highly potent neutralizing antibody against authentic variants WA1, D614G, Alpha, and Gamma that blocks ACE2 binding through an interaction with the RBD. The authors show that mAb-S5 is potent . . .

     

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