Induction of nlrp3 inflammasome activation by heme in human endothelial cells

HIGHLIGHTS

  • who: Judit Erdei and colleagues from the Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary , Orleans, France have published the Article: Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells, in the Journal: Oxidative Medicine and Cellular Longevity 5 of 20/03/2018
  • what: Next, the authors aimed to explore the structural motifs that are involved in hememediated inflammasome activation. The authors show that heme is an inducer of IL-1β processing through the activation of the NLRP3 inflammasome in human endothelial cells. The authors show that in contrast . . .

     

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