Induction of protection in mice against a respiratory challenge by a vaccine formulated with exosomes isolated from chlamydia muridarum infected cells

HIGHLIGHTS

• who: Sukumar Pal from the Immunization, challenge, and data collection Three-week old BALB/c (H-2d) mice were immunized with Cmuridarum- or control-exosomes, (, u03bcg/mouse/immunization), three times at two-week intervals by the intramuscular (i.m.) plus the subcutaneous (s.c.) routes. Cp, (, u00b5g/mouse/immunization) and Montanide ISA , VG (70:, v/v) were used as adjuvants21. Another negative control group was vaccinated with PBS adjuvanted as above following the same schedule. Four weeks after the final immunization, anesthetized mice were challenged i.n. with , IFU of C. muridarum and mice were weighed daily . . .
  

   

  

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