Induction of psoriasis- and atopic dermatitis-like phenotypes in 3d skin equivalents with a fibroblast-derived matrix

HIGHLIGHTS

• who: Bianka Morgner from the DepartmentUniversity Hospital have published the research work: Induction of psoriasis- and atopic dermatitis-like phenotypes in 3D skin equivalents with a fibroblast-derived matrix, in the Journal: Scientific Reports Scientific Reports

SUMMARY

In vitro mimicking of disease-associated phenotypes in 3D skin models was introduced upon subcutaneous stimulation with cytokines related to Th1/Th17 (briefly named as Th1 mix) and Th2 signalling. Haematoxylin and amp; eosin (HE) staining was performed to evaluate the morphological quality of the skin models. HE-stained skin models showed a well-layered microanatomy . . .

 



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